|
KMID : 0882420050680020215
|
|
Korean Journal of Medicine
2005 Volume.68 No. 2 p.215 ~ p.219
|
|
|
A case of primary pulmonary NK-cell lymphoma
|
|
Lee Jeong-Hoon
Huh Joo-Ryung
Kim Sang-We
Ko Ock-Bae
Yoon Soon-Man
Kang Yoon-Koo
Suh Chul-Won
|
|
|
Abstract
|
|
|
|
NK-cell lymphoma, distinct clinicopathologic entity, almost always occurs in the naso-sinal region. NK-cell lymphomas of other extranodal sites have also been recognized in previous case reports, but very rare. As far as we know, only four cases of primary pulmonary NK-cell lymphoma were reported wouldwide. We experienced a case of primary pulmonary NK-cell lymphoma. A 54-year-old man was admitted because of cough and chest discomfort. The chest CT shows multifocal ground-glass and nodular opacities in both lungs. Video Assisted Thoracoscopy (VATS) was performed to assess the lung lesion. The tumor cells were charcterized by cytoplasmic CD3 (+), CD56 (+), T-cell receptor antigen (-), Epstein-Barr Virus (+) and T-cell gene rearrangement (-), These findings were compatible with NK-cell lymphoma. So we performed the whole body Flurodeoxyglucose-Positron Emission Tomography (FDG-PET) to exclude any other lesion. The FDG-PET showed multiple hypermetabolic lesions only located in both lungs. The patient underwent 6 cycles of chemotherapy according to a CHOP regimen. Now his disease state is complete remission. To our knowledge, this is the first case of primary pulmonary NK-cell lymphoma in Korea.
|
|
|
KEYWORD
|
|
|
NK-cell Lymphoma, Primary pulmonary
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|